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KMID : 0377519840090040517
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Chung-Ang Journal of Medicine
1984 Volume.9 No. 4 p.517 ~ p.522
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Studies on the Carcinoembryonic Antigen and the Secertory Component in the Adenocarcinnoma of the Uterine Cervix
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Lee June-Woo
Ko Gee-Hyung
Yoo Jae-Hyung
Song Kye-Yong
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Abstract
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To observe the correlation between the carcinoembryonic antigen and the secretory component with their morphological differentiation in the adenocarcinoma, immunohistochemical studies were carried out with 46 cases of adenocarcinoma of the cervix. The study consists of 34 cases of the tubular type, 4 cases of the papillary type, 6 cases of the papillotubular type and 2 cases of the poorly differentiated signet ring cell type. The results were as follows; 1. CEA is positive in 85.3% of the tubular type and negative in 75% of the papillary type and focal positive in papillotubular and signet ring cells. 2. SC is positive in 58.8% of the tubular type and negative in 75% of the papillary type and focal positive in the papillotubular and negative in the signet ring cells. 3. The coincidence rate in both CEA and SC was 61.0% and the positive rate in either CEA or SC was 91.2% in the tubular adenocarcinoma. 75% of the papillary type was negative both in CEA and sc. Therefore, CEA and SC were positive in the majority of adenocarcinoma of uterine cervix, especially in the tubular type, where there was a close relationship with morphological differentiation, suggesting serial check of both CEA and SC in the tubular type was useful to treatment and prognosis. But papillary type and poorly differentiated signet ring cells were not consistent.
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